Research has enabled many people living with human immunodeficiency virus (HIV), the virus that causes acquired immunodeficiency syndrome (AIDS), to lead full, productive lives. As with other serious illnesses such as cancer, heart disease or stroke, HIV often can be accompanied by depression, a condition that can affect mind, mood, body, and behavior. Treatment for depression helps people manage both conditions, thus enhancing survival and quality of life. To learn more about HIV and mental health, please visit the Center for Disease Control.